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DTIC AD0675780: SURVIVAL TIME AND INCAPACITATION IN SUPRALETHALLY IRRADIATED DOGS

Incapacitation and resultant times of death have been studied with dogs following supralethal doses of either 60Co gamma or pulsed TRIGA reactor radiations. The nominal doses delivered were 4500, 9000, 13,500, or 18,000 rad. The exposure rates were 190.25 R/min from the 60Co sources and 3.4 - 11.5 x 10 to the 7th power rad/min from the TRIGA reactor. The two lower doses (4500 and 9000 rad) produced gastrointestinal deaths, with survival times ranging from 67 - 97.5 hours. These animals first exhibited signs of incapacitation at 48 - 72 hours. The two high doses (13,500 and 18,000 rad), on the other hand, produced central nervous system deaths, with survival times of 16 - 90.5 hours. With the exception of one animal, all dogs receiving 18,000 rad died within 29 hours. The dogs exposed to 13,500 rad had a much greater spread in survival times, indicating that doses in this range may cause either a gastrointestinal or central nervous system syndrome in dogs. All dogs in these two dose groups were incapacitated by 100 minutes. There was no evidence in the dogs of any recovery after the initial signs of incapacitation. The rate and severity of incapacitation was generally related to dos

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