English

Blastocyst cryopreservation using solid surface vitrification: A preliminary study.

This article is from Journal of Human Reproductive Sciences , volume 4 . Abstract OBJECTIVE:: The objective was to evaluate the effectiveness of a blastocyst cryopreservation program using solid surface vitrification. SETTING:: This study took place in a university teaching hospital. STUDY DESIGN:: Retrospective observational study. MATERIALS AND METHODS:: Women undergoing frozen embryo transfer cycles over a 4-year period between 2006 and 2010 were studied. The cryopreservation policy followed was a vitrification protocol performed at the blastocyst stage, using a solid surface (nonimmersion) method. The post-thaw survival rate, implantation rate, clinical pregnancy rate, live birth rate, and neonatal outcome were recorded. RESULTS:: Eighty-one women underwent 86 frozen embryo transfer cycles. Of the 240 blastocysts warmed, 204 survived giving a cryosurvival rate of 85% (204/240). The clinical pregnancy, implantation, miscarriage, ongoing pregnancy, and live birth rates per transfer were 47%, 29%, 12%, 16%, and 23% respectively. Of the 20 live births, there were 16 singletons and 4 twins. Eleven boys and 13 girls were delivered with no major or minor abnormality detected. CONCLUSI

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